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rel-VU6021625 is the relative configuration of VU6021625. VU6021625 is identified as a potent and selective mAChR M4 antagonist, exhibiting IC50 values of 0.44 nM for human M4 and 57 nM for rat M4. The product is intended for research use only.
Potent and selective mAChR M4 antagonist
Relative configuration of VU6021625
IC50 values: 0.44 nM (human M4), 57 nM (rat M4)
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MW 254.24 Da, Purity >99%. Antioxidant flavonoid. Anti-inflammatory and antioxidant properties, also able to induce apoptosis. Potent inhibitor of hypoxia-inducible factor 1α (HIF-1α).
MW 430.7 Da, Purity >98%. Fat-soluble antioxidant. Peroxyl radical scavenger that protects polyunsaturated fatty acids in membranes and lipoproteins. Anticarcinogen.
Vitamin K1 also known as phylloquinone is a fat-soluble vitamin found in algae nbspcyanobacteria and plants. It is involved in the synthesis of some important proteins having applications in blood clotting and bone metabolism.Vitamin K1-4a 5 6 7 8 8a-13C6 is an isotope of vitamin K1 wherein C-4a C-5 C-6 C-7 C-8 C-8a carbons are replaced by 13C6 carbon.
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MW 424.7 Da, Purity >98%. Form of vitamin E. Lipophilic antioxidant agent. Tocotrienol β (ab145176), δ (ab144449) and γ (ab144448) analog. Induces apoptosis in cancer cells. Shows antitumor, neuroprotective and antioxidant effects in vivo. Orally active.
An analog of 1,24-dihydroxy vitamin D3 which, when used in a 4 μg/g ointment, suppresses psoriasis; inhibits the growth of both normal and psoriatic human keratinocytes (IC50 ~ 10 nM) via the vitamin D receptor; suppresses the production of RANTES and IL-8 by human dermal fibroblasts
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